Your body map - Acanthosis Nigricans. A visible clue to hidden health concerns
Acanthosis nigricans (AN) is more than just a cosmetic skin condition. Characterized by dark, velvety patches typically appearing on areas like the neck, armpits, and groin, this condition often serves as an early indicator of deeper health issues. Dr. Chhaya Makhija, triple board-certified endocrinologist, highlights the significance of recognizing AN as a marker for underlying metabolic and hormonal imbalances, particularly insulin resistance.
What is Acanthosis Nigricans?
Acanthosis nigricans is a condition where the skin becomes thickened, darker, and velvety, often accompanied by mild itching or an unusual texture. While it may seem like a surface-level issue, it frequently points to more significant systemic problems.
Key Facts About AN:
Prevalence: AN is surprisingly common, affecting up to 50% of people over the age of 60. Certain ethinicities tend to have this finding such as South Asian Indians.
Primary Cause: The most common underlying factor is insulin resistance, which is often linked to obesity and type 2 diabetes.
Appearance: Dark, thickened, and velvety skin, commonly found on the neck, armpits, groin, and occasionally other body folds.
Associated Conditions: Besides diabetes, AN can signal conditions like polycystic ovary syndrome (PCOS), metabolic syndrome, prediabetes, and, in rare cases, certain cancers. Cushing’s syndrome can lead to hyperglycemia, insulin resistance and patients may have AN as a skin manifestation along with other specific signs for this disease.
Why Acanthosis Nigricans Shouldn't Be Ignored
Dr. Makhija emphasizes that AN is not just a cosmetic issue—it’s your body’s way of signaling that something deeper may be going on. It is often one of the first visible signs of metabolic syndrome, which can lead to:
Increased risk of type 2 diabetes.
Higher chances of developing heart disease.
Hormonal imbalances tied to conditions like PCOS.
For high-stress professionals, especially those in demanding environments like the Bay Area, AN may indicate that your body is struggling to regulate insulin due to poor dietary habits, lack of exercise, or chronic stress. Now, individuals may have AN at baseline and it becomes more prominent due to other contributing factors worsening insulin resistance.
Dr. Makhija’s Treatment Approach
Dr. Makhija focuses on addressing the root causes of acanthosis nigricans through a comprehensive and personalized approach:
1. Comprehensive Evaluation
A thorough assessment of hormonal and metabolic health to identify contributing factors like insulin resistance, obesity, or underlying thyroid or adrenal issues.
2. Lifestyle Modifications
Weight Loss: Sustainable weight loss through tailored diet and exercise plans is often the first line of treatment;
Dietary Adjustments: Focus on balanced meals with low glycemic index foods to stabilize blood sugar levels;
Physical Activity: Regular moderate exercise to improve insulin sensitivity and overall metabolic health;
Stress management: Addressing sleep habits and your habits related to responding to life stressors;
Supplements: Discussion of safe supplement options to treat deficiencies are an essential part of your care;
Referral to dermatologist: Skin finding of AN does not necessarily predict the laboratory abnormality or disease diagnosis, it is a manifestation and then workup is initiated. Similarly, treatment of metabolic disorder or diabetes-2 does not resolve AN, hence a dermatologist can assist with expertise for the cosmetic treatment.
3. Medications When Needed
In some cases, insulin-sensitizing medications like metformin may be prescribed to address the root cause of insulin resistance;
I also consider use of plant extract berberine in many patients.
4. Topical Treatments for Skin Appearance
For patients concerned about the cosmetic aspect of AN, Dr. Makhija may recommend dermatology referral for topical treatments such as retinoids or alpha-hydroxy acids to improve the skin’s texture and tone.
5. Ongoing Monitoring
Regular follow-ups are essential to track progress, adjust treatments, and prevent the development of more severe complications like type 2 diabetes or cardiovascular issues.
When to Seek Help
If you notice dark, velvety patches on your skin, particularly on your neck or underarms, it’s essential to act quickly—especially if you:
Are experiencing weight challenges;
Have a family history of diabetes;
Are noticing other symptoms like fatigue, increased thirst, or hormonal imbalances.
Dr. Makhija stresses that early detection and management are key. By addressing the underlying metabolic or hormonal issues, patients can often reverse or significantly improve both the appearance of their skin and their overall health.
Take Control of Your Health
Acanthosis nigricans is your body’s way of sending a signal—it’s time to listen. Don’t ignore this warning sign. Early intervention can:
Reduce your risk of type 2 diabetes and other complications;
Improve your skin’s appearance and texture;
Enhance your overall health and longevity.
Dr. Chhaya Makhija is here to help you take proactive steps toward better health. With her expertise in endocrine and metabolic health, she offers personalized care plans to address the root cause of AN and other related conditions.
📞 Call today to schedule a consultation: 559-272-9192
Convenient Options for Your Busy Lifestyle:
In-person appointments available in Lafayette (Bay Area) and Fresno offices (Clovis-Madera-Sanger-Selma-Merced-Visalia)
Telemedicine consultations offered throughout California
Whether you're a busy executive in Silicon Valley or a professional in Central California, Dr. Makhija's flexible scheduling ensures you can prioritize your health without compromising your career.
Don't wait for your health to become a crisis. Act now:
Schedule your comprehensive evaluation
Get a personalized treatment plan
Start your journey to optimal health and clear skin
Empower yourself with knowledge and take the first step toward healthier skin and a healthier you. Let Dr. Makhija guide you to the vibrant, energetic life you deserve.
Your health is your most valuable asset.